Description：

Clinafloxacin is a fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV dually in Streptococcus pneumoniae.

Chemical Information：

Molecular Weight (MW)		365.79
Formula		C17H17ClFN3O3
CAS No.		105956-97-6
Solubility (25°C) *	DMSO	0.03 mg/mL (0.08 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

wild-type BRAF BRAFV600E wild-type CRAF 100 nM 34 nM 29 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.7338 mL	13.6690 mL	27.3381 mL
5 mM	0.5468 mL	2.7338 mL	5.4676 mL
10 mM	0.2734 mL	1.3669 mL	2.7338 mL
50 mM	0.0547 mL	0.2734 mL	0.5468 mL

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