Description：

Cinacalcet HCl represents a new class of compounds for the treatment of hyperparathyroidism.

Chemical Information：

Molecular Weight (MW)		393.87
Formula		C22H22F3N.HCl
CAS No.		364782-34-3
Solubility (25°C) *	DMSO	79 mg/mL (200.57 mM)
	Water	Insoluble
	Alcohol	33 mg/mL (83.78 mM)

Biological Activity：

Targets IC50

Notch S3 cleavag γ-secreta γ-secreta 0.39 nM 0.078 nM (membr 0.082 nM (cell-

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.5389 mL	12.6945 mL	25.3891 mL
5 mM	0.5078 mL	2.5389 mL	5.0778 mL
10 mM	0.2539 mL	1.2695 mL	2.5389 mL
50 mM	0.0508 mL	0.2539 mL	0.5078 mL

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