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Description:
Cilomilast is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.
Chemical Information:
Molecular Weight (MW) 343.42 Formula
C20H25NO4
CAS No. 153259-65-5 Solubility (25°C) * DMSO 69 mg/mL (200.92 mM) Water Insoluble Alcohol 50 mg/mL (145.59 mM)
Biological Activity:
Targets IC50
TβRI TβRII 38 nM (Ki) 300 nM (Ki)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.9119 mL 14.5594 mL 29.1189 mL 5 mM 0.5824 mL 2.9119 mL 5.8238 mL 10 mM 0.2912 mL 1.4559 mL 2.9119 mL 50 mM 0.0582 mL 0.2912 mL 0.5824 mL
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