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Cilomilast

Cilomilast

Catalog Number: CC1611 Rank: comment rank 5

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$ 468.00
$ 84.00
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Description:

Cilomilast is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.

Chemical Information:

Molecular Weight (MW) 343.42
Formula

 

C20H25NO4

 

CAS No. 153259-65-5
Solubility (25°C) * DMSO 69 mg/mL (200.92 mM)
Water Insoluble
Alcohol 50 mg/mL (145.59 mM)


Biological Activity:

Targets
IC50
TβRI TβRII
38 nM (Ki) 300 nM (Ki)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.9119 mL 14.5594 mL 29.1189 mL
5 mM 0.5824 mL 2.9119 mL 5.8238 mL
10 mM 0.2912 mL 1.4559 mL 2.9119 mL
50 mM 0.0582 mL 0.2912 mL 0.5824 mL


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