Description：

Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with K_i of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively.

Chemical Information：

Molecular Weight (MW)		315.86
Formula		C18H18ClNS
CAS No.		113-59-7
Solubility (25°C) *	DMSO	6 mg/mL (18.99 mM)
	Water	Insoluble
	Alcohol	28 mg/mL (88.64 mM)

Biological Activity：

Targets IC50

HCT-116 Pol I MIA PaCa-2 A375 167 nM (ED50) 142 nM 74 nM (ED50) [1 58 nM (ED50)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.1660 mL	15.8298 mL	31.6596 mL
5 mM	0.6332 mL	3.1660 mL	6.3319 mL
10 mM	0.3166 mL	1.5830 mL	3.1660 mL
50 mM	0.0633 mL	0.3166 mL	0.6332 mL

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