Description：

Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively.

Chemical Information：

Molecular Weight (MW)		696.84
Formula		C30H28N6O6S4
CAS No.		28097-03-2
Solubility (25°C) *	DMSO	100 mg/mL warmed (143.5 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

Her-2 HSP90 37 nM 41 nM (Kd)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.4350 mL	7.1752 mL	14.3505 mL
5 mM	0.2870 mL	1.4350 mL	2.8701 mL
10 mM	0.1435 mL	0.7175 mL	1.4350 mL
50 mM	0.0287 mL	0.1435 mL	0.2870 mL

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