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Description:
Cephalothin is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.
Chemical Information:
Molecular Weight (MW) 418.42 Formula
C16H15N2NaO6S2
CAS No. 58-71-9 Solubility (25°C) * DMSO 10 mg/mL (23.89 mM) Water 83 mg/mL (198.36 mM) Alcohol Insoluble
Biological Activity:
Targets IC50
Src Abl PDGFR VEGFR2 Hck mTOR 14 nM 18 nM 2 nM 12 nM 8 nM 10 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.3899 mL 11.9497 mL 23.8994 mL 5 mM 0.4780 mL 2.3899 mL 4.7799 mL 10 mM 0.2390 mL 1.1950 mL 2.3899 mL 50 mM 0.0478 mL 0.2390 mL 0.4780 mL
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