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Cephalothin

Cephalothin

Catalog Number: CC4750 Rank: comment rank 5

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Description:

Cephalothin is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.

Chemical Information:

Molecular Weight (MW) 418.42
Formula

 

C16H15N2NaO6S2

 

CAS No. 58-71-9
Solubility (25°C) * DMSO 10 mg/mL (23.89 mM)
Water 83 mg/mL (198.36 mM)
Alcohol Insoluble


Biological Activity:

Targets
IC50
Src Abl PDGFR VEGFR2 Hck mTOR
14 nM 18 nM 2 nM 12 nM 8 nM 10 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.3899 mL 11.9497 mL 23.8994 mL
5 mM 0.4780 mL 2.3899 mL 4.7799 mL
10 mM 0.2390 mL 1.1950 mL 2.3899 mL
50 mM 0.0478 mL 0.2390 mL 0.4780 mL


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