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CB1954

CB1954

Catalog Number: CC7985 Rank: comment rank 5

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Description:

CB1954(Tretazicar) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. It can be activated by NAD(P)H quinone oxidoreductase 2.

Chemical Information:

Molecular Weight (MW) 252.18
Formula

 

C9H8N4O5

 

CAS No. 21919-05-1
Solubility (25°C) * DMSO 50 mg/mL (198.27 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.9654 mL 19.8271 mL 39.6542 mL
5 mM 0.7931 mL 3.9654 mL 7.9308 mL
10 mM 0.3965 mL 1.9827 mL 3.9654 mL
50 mM 0.0793 mL 0.3965 mL 0.7931 mL


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