Description：

Canertinib (CI-1033) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3.

Chemical Information：

Molecular Weight (MW)		485.94
Formula		C24H25ClFN5O3
CAS No.		267243-28-7
Solubility (25°C) *	DMSO	2 mg/mL (4.11 mM)
	Water	Insoluble
	Alcohol	9 mg/mL (18.52 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0579 mL	10.2893 mL	20.5787 mL
5 mM	0.4116 mL	2.0579 mL	4.1157 mL
10 mM	0.2058 mL	1.0289 mL	2.0579 mL
50 mM	0.0412 mL	0.2058 mL	0.4116 mL

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