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Cabotegravir (GSK744, GSK1265744)

Cabotegravir (GSK744, GSK1265744)

Catalog Number: CC7922 Rank: comment rank 5

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Description:

Cabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor against a broad range of HIV subtypes, and inhibits the HIV-1 integrase catalyzed strand transfer reaction with IC50 of 3.0 nM. Phase 2.

Chemical Information:

Molecular Weight (MW) 405.35
Formula

 

C19H17F2N3O5

 

CAS No. 1051375-10-0
Solubility (25°C) * DMSO 38 mg/mL warmed (93.74 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.4670 mL 12.3350 mL 24.6700 mL
5 mM 0.4934 mL 2.4670 mL 4.9340 mL
10 mM 0.2467 mL 1.2335 mL 2.4670 mL
50 mM 0.0493 mL 0.2467 mL 0.4934 mL


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