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Description:
BX912 is a potent and specific PDK1 inhibitor with IC50 of 12 nM, 9- and 105- fold greater selectivity for PDK1 than PKA and PKC in cell-free assays, respectively. In comparison to GSK3β, selectivity for PDK1 is 600-fold.
Chemical Information:
Molecular Weight (MW) 471.35 Formula
C20H23BrN8O
CAS No. 702674-56-4 Solubility (25°C) * DMSO 94 mg/mL (199.42 mM) Water Insoluble Alcohol 94 mg/mL (199.42 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.1216 mL 10.6078 mL 21.2157 mL 5 mM 0.4243 mL 2.1216 mL 4.2431 mL 10 mM 0.2122 mL 1.0608 mL 2.1216 mL 50 mM 0.0424 mL 0.2122 mL 0.4243 mL
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