Description：

Brivanib alaninate (BMS-582664) is the prodrug of BMS-540215, an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM.

Chemical Information：

Molecular Weight (MW)		441.46
Formula		C22H24FN5O4
CAS No.		649735-63-7
Solubility (25°C) *	DMSO	88 mg/mL (199.33 mM)
	Water	Insoluble
	Alcohol	88 mg/mL (199.33 mM)

Biological Activity：

Targets IC50

Cyclophilin MTP Calcineurin 7 nM 39 nM 7 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2652 mL	11.3261 mL	22.6521 mL
5 mM	0.4530 mL	2.2652 mL	4.5304 mL
10 mM	0.2265 mL	1.1326 mL	2.2652 mL
50 mM	0.0453 mL	0.2265 mL	0.4530 mL

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