Description：

Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM in cell-free assays, respectively.

Chemical Information：

Molecular Weight (MW)		530.45
Formula		C26H29Cl2N5O3
CAS No.		380843-75-4
Solubility (25°C) *	DMSO	100 mg/mL (188.51 mM)
	Water	Insoluble
	Alcohol	2 mg/mL (3.77 mM)

Biological Activity：

Targets IC50

Plk1 0.87 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8852 mL	9.4260 mL	18.8519 mL
5 mM	0.3770 mL	1.8852 mL	3.7704 mL
10 mM	0.1885 mL	0.9426 mL	1.8852 mL
50 mM	0.0377 mL	0.1885 mL	0.3770 mL

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