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Bortezomib (PS-341)

Bortezomib (PS-341)

Catalog Number: CC1169 Rank: comment rank 5

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Description:

Bortezomib (PS-341) is a potent 20S proteasome inhibitor with Ki of 0.6 nM. It exhibits favorable selectivity towards tumor cells over normal cells.

Chemical Information:

Molecular Weight (MW) 384.24
Formula

 

C19H25BN4O4

 

CAS No. 179324-69-7
Solubility (25°C) * DMSO 76 mg/mL (197.79 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
TβRI
56 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.6025 mL 13.0127 mL 26.0254 mL
5 mM 0.5205 mL 2.6025 mL 5.2051 mL
10 mM 0.2603 mL 1.3013 mL 2.6025 mL
50 mM 0.0521 mL 0.2603 mL 0.5205 mL


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