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BMS-911543

BMS-911543

Catalog Number: CC7300 Rank: comment rank 5

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$ 118.00
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Description:

BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.

Chemical Information:

Molecular Weight (MW) 432.52
Formula

 

C23H28N8O

 

CAS No. 1271022-90-2
Solubility (25°C) * DMSO 36 mg/mL (83.23 mM)
Water Insoluble
Alcohol 22 mg/mL (50.86 mM)


Biological Activity:

Targets
IC50
p110δ
2.5 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.3120 mL 11.5602 mL 23.1203 mL
5 mM 0.4624 mL 2.3120 mL 4.6241 mL
10 mM 0.2312 mL 1.1560 mL 2.3120 mL
50 mM 0.0462 mL 0.2312 mL 0.4624 mL


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