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Description:
BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.
Chemical Information:
Molecular Weight (MW) 432.52 Formula
C23H28N8O
CAS No. 1271022-90-2 Solubility (25°C) * DMSO 36 mg/mL (83.23 mM) Water Insoluble Alcohol 22 mg/mL (50.86 mM)
Biological Activity:
Targets IC50
p110δ 2.5 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.3120 mL 11.5602 mL 23.1203 mL 5 mM 0.4624 mL 2.3120 mL 4.6241 mL 10 mM 0.2312 mL 1.1560 mL 2.3120 mL 50 mM 0.0462 mL 0.2312 mL 0.4624 mL
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