Description：

BMS-582949 is a potent and selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor with IC50 of 13nM,inhibiting both p38 kinase activity and activation of p38.

Chemical Information：

Molecular Weight (MW)		406.48
Formula		C22H26N6O2
CAS No.		623152-17-0
Solubility (25°C) *	DMSO	81 mg/mL (199.27 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

JAK2 JAK3 JAK1 18 nM 155 nM 11 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4601 mL	12.3007 mL	24.6015 mL
5 mM	0.4920 mL	2.4601 mL	4.9203 mL
10 mM	0.2460 mL	1.2301 mL	2.4601 mL
50 mM	0.0492 mL	0.2460 mL	0.4920 mL

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