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Description:
BMS-536924 is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2.
Chemical Information:
Molecular Weight (MW) 479.96 Formula
C25H26ClN5O3
CAS No. 468740-43-4 Solubility (25°C) * DMSO 96 mg/mL (200.01 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
mTOR 8 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.0835 mL 10.4175 mL 20.8351 mL 5 mM 0.4167 mL 2.0835 mL 4.1670 mL 10 mM 0.2084 mL 1.0418 mL 2.0835 mL 50 mM 0.0417 mL 0.2084 mL 0.4167 mL
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