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BLZ945

BLZ945

Catalog Number: CC7881 Rank: comment rank 5

Size Price Qty
$ 137.00
$ 417.00
$ 697.00
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Description:

BLZ945 is an orally active, potent and selective CSF-1R inhibitor with IC50 of 1 nM, >1000-fold selective against its closest receptor tyrosine kinase homologs.

Chemical Information:

Molecular Weight (MW) 398.48
Formula

 

C20H22N4O3S

 

CAS No. 953769-46-5
Solubility (25°C) * DMSO 79 mg/mL (198.25 mM)
Water Insoluble
Alcohol 3 mg/mL warmed (7.52 mM)


Biological Activity:

Targets
IC50
p110β p110δ p110γ p110α
25 μM 0.24 μM 10 μM 100 μM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.5095 mL 12.5477 mL 25.0954 mL
5 mM 0.5019 mL 2.5095 mL 5.0191 mL
10 mM 0.2510 mL 1.2548 mL 2.5095 mL
50 mM 0.0502 mL 0.2510 mL 0.5019 mL


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