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Description:
BLU-554 is a potent, highly-selective, oral FGFR4 inhibitor with an IC50 value of 5 nM. The IC50s for FGFR1-3 is 624-2203 nM.
Chemical Information:
Molecular Weight (MW) 503.38 Formula
C24H24Cl2N4O4
CAS No. 1707289-21-1 Solubility (25°C) * DMSO 100 mg/mL warmed (198.65 mM) Water Insoluble Alcohol 2 mg/mL warmed (3.97 mM)
Biological Activity:
Targets IC50
EGFR 2 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.9866 mL 9.9329 mL 19.8657 mL 5 mM 0.3973 mL 1.9866 mL 3.9731 mL 10 mM 0.1987 mL 0.9933 mL 1.9866 mL 50 mM 0.0397 mL 0.1987 mL 0.3973 mL
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