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Description:
BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM in a cell-free assay. No inhibition of DNA and RNA polymerases, including HIV reverse transcriptase were observed at concentrations vastly exceeding the IC50 for telomerase.
Chemical Information:
Molecular Weight (MW) 331.36 Formula
C21H17NO3
CAS No. 321674-73-1 Solubility (25°C) * DMSO 66 mg/mL (199.17 mM) Water Insoluble Alcohol 3 mg/mL (9.05 mM)
Biological Activity:
Targets IC50
GK 42 nM (EC50) [1
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.0179 mL 15.0893 mL 30.1787 mL 5 mM 0.6036 mL 3.0179 mL 6.0357 mL 10 mM 0.3018 mL 1.5089 mL 3.0179 mL 50 mM 0.0604 mL 0.3018 mL 0.6036 mL
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