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Endocrinology & Hormones >
Estrogen/progestogen Receptor modulator >
Bazedoxifene HCl
Description:
Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectively.
Chemical Information:
Molecular Weight (MW) 507.06 Formula
C30H34N2O3.HCl
CAS No. 198480-56-7 Solubility (25°C) * DMSO 101 mg/mL (199.18 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
COX-1 COX-2 13 μM 370 μM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.9722 mL 9.8608 mL 19.7215 mL 5 mM 0.3944 mL 1.9722 mL 3.9443 mL 10 mM 0.1972 mL 0.9861 mL 1.9722 mL 50 mM 0.0394 mL 0.1972 mL 0.3944 mL
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