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Description:
Ac-DEVD-CHO is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2.
Chemical Information:
Molecular Weight (MW) 502.47 Formula
C20H30N4O11
CAS No. 169332-60-9 Solubility (25°C) * DMSO Water 100 mg/mL (199.01 mM) Alcohol
Biological Activity:
Targets IC50
p110α mTOR p110δ p110γ DNA-PK p110β 2 nM 30 nM 3 nM 15 nM 23 nM 3 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.9902 mL 9.9508 mL 19.9017 mL 5 mM 0.3980 mL 1.9902 mL 3.9803 mL 10 mM 0.1990 mL 0.9951 mL 1.9902 mL 50 mM 0.0398 mL 0.1990 mL 0.3980 mL
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