Description：

BAY 1217389 is an orally bioavailable, selective inhibitor of the serine/threonine kinase monopolar spindle 1 (Mps1) with IC50 values below 10 nmol/L while showing an excellent selectivity profile.

Chemical Information：

Molecular Weight (MW)		561.50
Formula		C27H24F5N5O3
CAS No.		1554458-53-5
Solubility (25°C) *	DMSO	100 mg/mL (178.09 mM)
	Water	Insoluble
	Alcohol	3 mg/mL warmed (5.34 mM)

Biological Activity：

Targets IC50

Human Factor Xa Rabbit Factor X 0.08 nM (Ki) 0.17 nM (Ki) [1

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7809 mL	8.9047 mL	17.8094 mL
5 mM	0.3562 mL	1.7809 mL	3.5619 mL
10 mM	0.1781 mL	0.8905 mL	1.7809 mL
50 mM	0.0356 mL	0.1781 mL	0.3562 mL

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