Description：

BAW2881 (NVP-BAW2881) is a novel vascular endothelial growth factor (VEGF) receptor tyrosine-kinase inhibitor that potently inhibits VEGFR1-3 at 1.0-4.3 nanomolar (nM) concentrations and inhibits PDGFRβ, c-Kit, and RET at 45-72 nM concentrations.

Chemical Information：

Molecular Weight (MW)		424.38
Formula		C22H15F3N4O2
CAS No.		861875-60-7
Solubility (25°C) *	DMSO	84 mg/mL (197.93 mM)
	Water	Insoluble
	Alcohol	20 mg/mL (47.12 mM)

Biological Activity：

Targets IC50

CDK6 CDK4 16 nM 11 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3564 mL	11.7819 mL	23.5638 mL
5 mM	0.4713 mL	2.3564 mL	4.7128 mL
10 mM	0.2356 mL	1.1782 mL	2.3564 mL
50 mM	0.0471 mL	0.2356 mL	0.4713 mL

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