Description：

Barasertib (AZD1152-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, ~3700 fold more selective for Aurora B over Aurora A. Phase 1.

Chemical Information：

Molecular Weight (MW)		507.56
Formula		C26H30FN7O3
CAS No.		722544-51-6
Solubility (25°C) *	DMSO	102 mg/mL (200.96 mM)
	Water	Insoluble
	Alcohol	3 mg/mL (5.91 mM)

Biological Activity：

Targets IC50

p38α MAPK 0.1 nM (Kd)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9702 mL	9.8511 mL	19.7021 mL
5 mM	0.3940 mL	1.9702 mL	3.9404 mL
10 mM	0.1970 mL	0.9851 mL	1.9702 mL
50 mM	0.0394 mL	0.1970 mL	0.3940 mL

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