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Description:
Bacitracin is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.
Chemical Information:
Molecular Weight (MW) 1486.07 Formula
C66H101N17O16SZn
CAS No. 1405-89-6 Solubility (25°C) * DMSO 0.15 mg/mL (0.1 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
PDPK1 Akt 5.2 μM 2.7 μM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 0.6729 mL 3.3646 mL 6.7292 mL 5 mM 0.1346 mL 0.6729 mL 1.3458 mL 10 mM 0.0673 mL 0.3365 mL 0.6729 mL 50 mM 0.0135 mL 0.0673 mL 0.1346 mL
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