Description：

ZK756326 is a full agonist of CCR8（Chemokine receptor 8） with an IC50 of 1.8 μM, dose-responsively eliciting an increase in intracellular calcium and cross-desensitizing the response of the receptor to CCL1.

Chemical Information：

Molecular Weight (MW)		429.38
Formula		C21H28N2O3.2HCl
CAS No.		874911-96-3
Solubility (25°C) *	DMSO	39 mg/mL (90.82 mM)
	Water	78 mg/mL (181.65 mM)
	Alcohol	4 mg/mL (9.31 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3289 mL	11.6447 mL	23.2894 mL
5 mM	0.4658 mL	2.3289 mL	4.6579 mL
10 mM	0.2329 mL	1.1645 mL	2.3289 mL
50 mM	0.0466 mL	0.2329 mL	0.4658 mL

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