Description：

3BDO, a butyrolactone derivative, could target FKBP1A and activate the mTOR signaling pathway, which inhibits autophagy in HUVECs.

Chemical Information：

Molecular Weight (MW)		327.33
Formula		C18H17NO5
CAS No.		890405-51-3
Solubility (25°C) *	DMSO	65 mg/mL (198.57 mM)
	Water	14 mg/mL (42.77 mM)
	Alcohol	49 mg/mL (149.69 mM)

Biological Activity：

Targets IC50

CB2 CB1 3.4 nM (Ki) 280 nM (Ki) [1

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.0550 mL	15.2751 mL	30.5502 mL
5 mM	0.6110 mL	3.0550 mL	6.1100 mL
10 mM	0.3055 mL	1.5275 mL	3.0550 mL
50 mM	0.0611 mL	0.3055 mL	0.6110 mL

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