Description：

Zibotentan (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.

Chemical Information：

Molecular Weight (MW)		424.43
Formula		C19H16N6O4S
CAS No.		186497-07-4
Solubility (25°C) *	DMSO	24 mg/mL (56.54 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3561 mL	11.7805 mL	23.5610 mL
5 mM	0.4712 mL	2.3561 mL	4.7122 mL
10 mM	0.2356 mL	1.1781 mL	2.3561 mL
50 mM	0.0471 mL	0.2356 mL	0.4712 mL

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