Description：

XL413 (BMS-863233) is a potent and selective cell division cycle 7 homolog (CDC7) kinase inhibitor with IC50 of 3.4 nM, showing 63-, 12- and 35-fold selectivity over CK2, Pim-1 and pMCM2, respectively. Phase 1/2.

Chemical Information：

Molecular Weight (MW)		326.18
Formula		C14H13Cl2N3O2
CAS No.		1169562-71-3
Solubility (25°C) *	DMSO	Insoluble
	Water	46 mg/mL warmed (141.02 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.0658 mL	15.3290 mL	30.6579 mL
5 mM	0.6132 mL	3.0658 mL	6.1316 mL
10 mM	0.3066 mL	1.5329 mL	3.0658 mL
50 mM	0.0613 mL	0.3066 mL	0.6132 mL

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