Description：

XL147 analogue is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. Phase 1/2.

Chemical Information：

Molecular Weight (MW)		448.52
Formula		C21H16N6O2S2
CAS No.		956958-53-5
Solubility (25°C) *	DMSO	3 mg/mL (6.68 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2296 mL	11.1478 mL	22.2955 mL
5 mM	0.4459 mL	2.2296 mL	4.4591 mL
10 mM	0.2230 mL	1.1148 mL	2.2296 mL
50 mM	0.0446 mL	0.2230 mL	0.4459 mL

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