Description：

WZ4002 is a novel, mutant-selective EGFR inhibitor for EGFR(L858R)/(T790M) with IC50 of 2 nM/8 nM in BaF3 cell line; does not inhibit ERBB2 phosphorylation (T798I).

Chemical Information：

Molecular Weight (MW)		494.18
Formula		C25H27ClN6O3
CAS No.		1213269-23-8
Solubility (25°C) *	DMSO	13 mg/mL (26.3 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0236 mL	10.1178 mL	20.2355 mL
5 mM	0.4047 mL	2.0236 mL	4.0471 mL
10 mM	0.2024 mL	1.0118 mL	2.0236 mL
50 mM	0.0405 mL	0.2024 mL	0.4047 mL

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