Description：

WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. Phase 1.

Chemical Information：

Molecular Weight (MW)		356.22
Formula		C17H14BrN3O
CAS No.		857064-38-1
Solubility (25°C) *	DMSO	71 mg/mL (199.31 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.8073 mL	14.0363 mL	28.0725 mL
5 mM	0.5615 mL	2.8073 mL	5.6145 mL
10 mM	0.2807 mL	1.4036 mL	2.8073 mL
50 mM	0.0561 mL	0.2807 mL	0.5615 mL

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