Description：

WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM, no activity against JAK1 or JAK2, also inhibits EGFR, Src, Abl, VEGFR and MAPK, prevents Stat3, but not Stat5 phosphorylation.

Chemical Information：

Molecular Weight (MW)		376.2
Formula		C16H14BrN3O3
CAS No.		211555-04-3
Solubility (25°C) *	DMSO	75 mg/mL (199.36 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6582 mL	13.2908 mL	26.5816 mL
5 mM	0.5316 mL	2.6582 mL	5.3163 mL
10 mM	0.2658 mL	1.3291 mL	2.6582 mL
50 mM	0.0532 mL	0.2658 mL	0.5316 mL

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