Description：

WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.

Chemical Information：

Molecular Weight (MW)		568.67
Formula		C32H36N6O4
CAS No.		837422-57-8
Solubility (25°C) *	DMSO	12 mg/mL warmed (21.1 mM)
	Water	Insoluble
	Alcohol	6 mg/mL warmed (10.55 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7585 mL	8.7924 mL	17.5849 mL
5 mM	0.3517 mL	1.7585 mL	3.5170 mL
10 mM	0.1758 mL	0.8792 mL	1.7585 mL
50 mM	0.0352 mL	0.1758 mL	0.3517 mL

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