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Description:
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
Chemical Information:
Molecular Weight (MW) 494.59 Formula
C28H30N8O
CAS No. 1062159-35-6 Solubility (25°C) * DMSO 22 mg/mL (44.48 mM) Water Insoluble Alcohol 2 mg/mL (4.04 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.0219 mL 10.1094 mL 20.2188 mL 5 mM 0.4044 mL 2.0219 mL 4.0438 mL 10 mM 0.2022 mL 1.0109 mL 2.0219 mL 50 mM 0.0404 mL 0.2022 mL 0.4044 mL
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