Description：

VX-745 is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.

Chemical Information：

Molecular Weight (MW)		436.26
Formula		C19H9Cl2F2N3OS
CAS No.		209410-46-8
Solubility (25°C) *	DMSO	15 mg/mL (34.38 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2922 mL	11.4611 mL	22.9221 mL
5 mM	0.4584 mL	2.2922 mL	4.5844 mL
10 mM	0.2292 mL	1.1461 mL	2.2922 mL
50 mM	0.0458 mL	0.2292 mL	0.4584 mL

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