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VS-5584 (SB2343)

VS-5584 (SB2343)

Catalog Number: CC7172 Rank: comment rank 5

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Description:

VS-5584 (SB2343) is a potent and selective dual PI3K/mTOR inhibitor for mTOR, PI3Kα/β/δ/γ with IC50 of 3.4 nM and 2.6-21 nM, respectively. Phase 1.

Chemical Information:

Molecular Weight (MW) 354.41
Formula

 

C17H22N8O

 

CAS No. 1246560-33-7
Solubility (25°C) * DMSO 71 mg/mL (200.33 mM)
Water Insoluble
Alcohol 3 mg/mL (8.46 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.8216 mL 14.1080 mL 28.2159 mL
5 mM 0.5643 mL 2.8216 mL 5.6432 mL
10 mM 0.2822 mL 1.4108 mL 2.8216 mL
50 mM 0.0564 mL 0.2822 mL 0.5643 mL


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