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Description:
Voxtalisib (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.
Chemical Information:
Molecular Weight (MW) 270.29 Formula
C13H14N6O
CAS No. 934493-76-2 Solubility (25°C) * DMSO 54 mg/mL (199.78 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.6997 mL 18.4986 mL 36.9973 mL 5 mM 0.7399 mL 3.6997 mL 7.3995 mL 10 mM 0.3700 mL 1.8499 mL 3.6997 mL 50 mM 0.0740 mL 0.3700 mL 0.7399 mL
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