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Voxtalisib (SAR245409, XL765) Analogue

Voxtalisib (SAR245409, XL765) Analogue

Catalog Number: CC1679 Rank: comment rank 5

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Description:

Voxtalisib (SAR245409, XL765) Analogue is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.

Chemical Information:

Molecular Weight (MW) 599.66
Formula

 

C31H29N5O6S

 

CAS No. 1349796-36-6
Solubility (25°C) * DMSO 12 mg/mL (20.01 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.6676 mL 8.3381 mL 16.6761 mL
5 mM 0.3335 mL 1.6676 mL 3.3352 mL
10 mM 0.1668 mL 0.8338 mL 1.6676 mL
50 mM 0.0334 mL 0.1668 mL 0.3335 mL


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