Description：

Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.

Chemical Information：

Molecular Weight (MW)		379.36
Formula		C18H22N2S.HBr
CAS No.		960203-27-4
Solubility (25°C) *	DMSO	76 mg/mL (200.33 mM)
	Water	Insoluble
	Alcohol	17 mg/mL (44.81 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6360 mL	13.1801 mL	26.3602 mL
5 mM	0.5272 mL	2.6360 mL	5.2720 mL
10 mM	0.2636 mL	1.3180 mL	2.6360 mL
50 mM	0.0527 mL	0.2636 mL	0.5272 mL

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