Description：

Vonoprazan Fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. Phase 3.

Chemical Information：

Molecular Weight (MW)		461.46
Formula		C17H16FN3O2S.C4H4O4
CAS No.		1260141-27-2
Solubility (25°C) *	DMSO	62 mg/mL (134.35 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1670 mL	10.8352 mL	21.6704 mL
5 mM	0.4334 mL	2.1670 mL	4.3341 mL
10 mM	0.2167 mL	1.0835 mL	2.1670 mL
50 mM	0.0433 mL	0.2167 mL	0.4334 mL

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