Description：

Volasertib (BI 6727) is a highly potent Plk1 inhibitor with IC50 of 0.87 nM in a cell-free assay. It shows 6- and 65-fold greater selectivity against Plk2 and Plk3. Phase 3.

Chemical Information：

Molecular Weight (MW)		618.81
Formula		C34H50N8O3
CAS No.		755038-65-4
Solubility (25°C) *	DMSO	20 mg/mL warmed (32.32 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.6160 mL	8.0800 mL	16.1600 mL
5 mM	0.3232 mL	1.6160 mL	3.2320 mL
10 mM	0.1616 mL	0.8080 mL	1.6160 mL
50 mM	0.0323 mL	0.1616 mL	0.3232 mL

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