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Description:
Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of <0.01 nM in cell-free assays, >4800-fold more selective versus Bcl-xL and Bcl-w, and no activity to Mcl-1. Phase 3.
Chemical Information:
Molecular Weight (MW) 868.44 Formula
C45H50ClN7O7S
CAS No. 1257044-40-8 Solubility (25°C) * DMSO 100 mg/mL warmed (115.14 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.1515 mL 5.7575 mL 11.5149 mL 5 mM 0.2303 mL 1.1515 mL 2.3030 mL 10 mM 0.1151 mL 0.5757 mL 1.1515 mL 50 mM 0.0230 mL 0.1151 mL 0.2303 mL
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