Description：

Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-Raf^V600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-Raf^V600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold.

Chemical Information：

Molecular Weight (MW)		489.92
Formula		C23H18ClF2N3O3S
CAS No.		918504-65-1
Solubility (25°C) *	DMSO	97 mg/mL (197.99 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0411 mL	10.2057 mL	20.4115 mL
5 mM	0.4082 mL	2.0411 mL	4.0823 mL
10 mM	0.2041 mL	1.0206 mL	2.0411 mL
50 mM	0.0408 mL	0.2041 mL	0.4082 mL

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