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Description:
Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2. Phase 3.
Chemical Information:
Molecular Weight (MW) 244.29 Formula
C13H16N4O
CAS No. 912444-00-9 Solubility (25°C) * DMSO 17 mg/mL (69.58 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 4.0935 mL 20.4675 mL 40.9350 mL 5 mM 0.8187 mL 4.0935 mL 8.1870 mL 10 mM 0.4093 mL 2.0467 mL 4.0935 mL 50 mM 0.0819 mL 0.4093 mL 0.8187 mL
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