Description：

Vatalanib (PTK787) 2HCl is an inhibitor of VEGFR2/KDR with IC50 of 37 nM in a cell-free assay, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. Phase 3.

Chemical Information：

Molecular Weight (MW)		419.73
Formula		C20H15ClN4.2HCl
CAS No.		212141-51-0
Solubility (25°C) *	DMSO	85 mg/mL (202.51 mM)
	Water	10 mg/mL (23.82 mM)
	Alcohol	6 mg/mL (14.29 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3825 mL	11.9124 mL	23.8248 mL
5 mM	0.4765 mL	2.3825 mL	4.7650 mL
10 mM	0.2382 mL	1.1912 mL	2.3825 mL
50 mM	0.0476 mL	0.2382 mL	0.4765 mL

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