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Uprosertib (GSK2141795)

Uprosertib (GSK2141795)

Catalog Number: CC7648 Rank: comment rank 5

Size Price Qty
$ 277.00
$ 627.00
$ 81.00
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Description:

Uprosertib (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.

Chemical Information:

Molecular Weight (MW) 429.25
Formula

 

C18H16Cl2F2N4O2

 

CAS No. 1047634-65-0
Solubility (25°C) * DMSO 85 mg/mL (198.01 mM)
Water Insoluble
Alcohol 85 mg/mL (198.01 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.3296 mL 11.6482 mL 23.2964 mL
5 mM 0.4659 mL 2.3296 mL 4.6593 mL
10 mM 0.2330 mL 1.1648 mL 2.3296 mL
50 mM 0.0466 mL 0.2330 mL 0.4659 mL


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