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Description:
UNC3866 is a potent antagonist of the methyllysine (Kme) reading function of the Polycomb CBX and CDY families of chromodomains. UNC3866 binds the chromodomains of CBX4 and CBX7 most potently, with a K(d) of ∼100 nM for each, and is 6- to 18-fold selective as compared to seven other CBX and CDY chromodomains.
Chemical Information:
Molecular Weight (MW) 795.02 Formula
C43H66N6O8
CAS No. 1872382-47-2 Solubility (25°C) * DMSO 100 mg/mL (125.78 mM) Water Insoluble Alcohol 46 mg/mL (57.86 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.2578 mL 6.2891 mL 12.5783 mL 5 mM 0.2516 mL 1.2578 mL 2.5157 mL 10 mM 0.1258 mL 0.6289 mL 1.2578 mL 50 mM 0.0252 mL 0.1258 mL 0.2516 mL
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