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Description:
UNC2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.
Chemical Information:
Molecular Weight (MW) 513.12 Formula
C28H41ClN6O
CAS No. 1429881-91-3(free base) Solubility (25°C) * DMSO 25 mg/mL warmed (48.72 mM) Water 100 mg/mL (194.88 mM) Alcohol 8 mg/mL warmed (15.59 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.9489 mL 9.7443 mL 19.4886 mL 5 mM 0.3898 mL 1.9489 mL 3.8977 mL 10 mM 0.1949 mL 0.9744 mL 1.9489 mL 50 mM 0.0390 mL 0.1949 mL 0.3898 mL
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